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Living with Irritable Bowel Syndrome

Saturday, December 08, 2007

Living with Irritable Bowel Syndrome.

HLE 11th September 2006

Dr. Andrew Thillainayagam, Consultant gastroenterologist at Charing Cross Hospital.

Irritable Bowel Syndrome (IBS) is a very common condition, affecting as many as one in five people at some time in their lives. It is not a disease, it is a collection of signs and symptoms due to an abnormality of function and, because it is an abnormality of function, you would see no abnormality, for example in a post mortem examination. It is simply that the system is not behaving normally. Symptoms vary widely and include abdominal pain, bloating, diarrhoea and/or constipation. It can cause patients considerable distress and seriously diminish their quality of life, but it is not a life-threatening condition.  However, similar symptoms can be due to other serious disorders, such as colorectal cancer and Crohn’s disease, so that it is essential for doctors to consider these possibilities in order to exclude them.

Although we know that patients suffering from IBS have some abnormality of the system and we can identify the condition if it satisfies well-recognised international criteria, we do not know exactly what is going on.  We do not know cause and effect but we can identify some of the precipitating factors, for example IBS can be triggered by a life event, or by suppressed physical or sexual abuse; in a small group of cases it can be food related, due to food intolerance (which is not the same thing as an allergy). Many adults are lactose intolerant, no doubt because mankind is not designed to drink milk after the baby stage! And stress can be an important precipitating factor as the mind and the gut are inter-related although we do not exactly know how.

Until comparatively recently there was no treatment for IBS. We now have the technology to enable us to investigate the disorder more thoroughly. We can stimulate the brain to see how the gut reacts and we can stimulate the gut to see how the brain reacts, but we are still seeking answers. Real research requires hard work.

Investigations are complicated as there are more than five metres of intestine and five different receptors. Because the receptors are non specific it is difficult to identify the source of pan, which may be anywhere in the intestine. In our present state of knowledge, it is as if we had taken the back of the television set and can see all the wires but we don’t know what they do!

However, we can treat some of the symptoms, such as diarrhoea, by the use of medication to slow down the gut, and constipation by medication or by recommending dietary changes.  A healthy life-style should include eating five portions of fruit and vegetables every day and drinking two and a half litres of water. Other treatments include hypnotherapy, acupuncture and cogitative therapy. Treatment by targeting serotonin is only used in the USA and is not available here.

Most patients are looked after by their GPs, or they are able to cope with the symptoms without professional help. It is only when the symptoms seriously interfere with the quality of life that patients are referred to a consultant. As a result, relatively few patients are seen by consultant gastroenterologists.

Questions and answers

Dr. Thillainayagam said life style and environment played a very big part in controlling the potentially devastating phenomena of IBS. He again emphasized that a healthy life-style was of utmost importance.

Another questioner asked when you should go to the doctor if you thought you might be suffering from IBS to discuss possible symptoms. Dr.Thillainayagam said that you should trust your instincts.

Dr. Thillainayagam ended by saying that research into cause and effect and treatment for IBS was making some progress but that there was much more hard work to be done before we could claim to have found satisfactory answers to the problems raised by this complicated disorder.

The Patients’ Group would like to thank Dr. Thillainayagam for taking the time out of his schedule to present his extremely informative and detailed talk.

Henry Palmer

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